10 Over-the-Counter Oral Antihistamine Brands We Love


When you have an allergic reaction, your body bonds with histamine–and while it is generally beneficial to release it every time you exercise or eat, when you’re caught off guard none-too-luckily, it can be absolutely horrible. Fortunately, there are lots of great over-the-counter antihistamines out there that work to reduce the swelteringly hot rashes and sneezing fit. We’ve rounded up 10 of our favorites for you!

Why Antihistamine Treatment Works

When you catch a cold, your immune system goes into overdrive in an effort to fight off the infection. This process could leave you feeling congested and a little itchy. In fact, according to the National Institutes of Health, over-the-counter (OTC) oral antihistamines are one of the most common medicines used to treat a cold.

The reason OTC oral antihistamines work is because they mimic the effects of histamine, which is a chemical your body produces in response to an infection. Histamine is responsible for making you feel congested and itchy. By blocking histamine receptors on your cells, OTC oral antihistamines allow your body to function normally without experiencing these symptoms.

So if you’re feeling run down and want to take an OTC medication to help relieve your symptoms, be sure to choose one of the brands we love below!

Types of allergic reactions

There are numerous over-the-counter (OTC) oral antihistamines on the market that can help individuals suffering from allergies. Allergic reactions can vary in severity, and some people may only need a minimal amount of an OTC oral antihistamine to manage their symptoms.

Some of the most popular OTC oral antihistamines include Allegra, Claritin, Zyrtec, and Benadryl. Each OTC oral antihistamine has its own specific benefits and drawbacks. For example, Allegra is a more severe histamine blocker than some of the other OTC oral antihistamines, while Claritin is less effective at blocking histamines but is more popular due to its milder effects.

Deciding which OTC oral antihistamine to take depends on the individual’s allergy symptoms and reaction severity. It’s important to speak with a doctor or allergy specialist if you’re not sure which OTC oral antihistamine is best for you.

How to take over-the-counter medication

If you’re feeling symptoms of a cold or the flu, there are several over-the-counter oral antihistamines that you can take to relieve your symptoms.

There are two types of over-the-counter oral antihistamines: those that are taken orally and those that are taken inhaled. Oral antihistamines are usually taken with water, but some people also take them with juice or soft drinks. Inhaled antihistamines are usually sprayed in the nose or mouth.

Before taking any oral or inhaled over-the-counter medication, be sure to read the instructions carefully. Some medications should not be used by pregnant women or children, and others should not be taken if you have certain medical conditions.

Over-the-counter oral antihistamines are a safe and effective way to relieve symptoms of a cold or the flu. Be sure to read the instructions carefully before using them, and don’t hesitate to ask your doctor if you have any questions about taking over-the-counter medication.

Top 10 Over the Counter Oral Antihistamine Brands

Do you suffer from allergies or hypersensitivity?

If so, you know that taking an over-the-counter oral antihistamine can be a life-saving measure in the event of an allergen emergency. Unfortunately, not all over-the-counter oral antihistamines are created equal. Here are our top 10 favorite over-the-counter oral antihistamines:

1. Claritin® D (Claritin D)
2. Allegra® D (Allegra D)
3. Zyrtec® OTC (Zyrtec OTC)
4. Allegra-D® SR (Allegra DS)
5. Benadryl® OTC (Benadryl OTC)
6. Claritin® A (Claritin A)
7. Pepcid AC (Simpson Syndrome, Gastroesophageal Reflux Disease, etc.)
8. Zyrtec ® HDS (Zyrtec HDS)
9. Nasacort nasal spray (Nasacort nasal spray)
10. Claritin® XL Singles Formula (Clarit

Comparisons and Reviews

There are many over-the-counter oral antihistamine brands out there, but which ones do we love? Here are some comparisons and reviews of some of our favorites.

Zyrtec is a brand of over-the-counter oral antihistamines that is well known for its effectiveness in relieving the symptoms of hay fever and other allergies. Reviews from users note that the medication works very quickly to relieve the symptoms and does not cause drowsiness or headache. One user said, “I cannot believe how much better my life is with Zyrtec! I wake up so refreshed and don’t have any allergy symptoms.”

Common cold sufferers may want to try NyQuil, another well-known over-the-counter oral antihistamine. This medication is often used to treat a wide variety of illnesses, including the common cold. Reviews from users note that NyQuil is effective in relieving cold symptoms and does not cause drowsiness. One satisfied user said, “NyQuil knocks the snot out of a cold!”

If you have seasonal allergies, Allegra is a good choice for you. Allegra is available as an over-the-counter medication as well as


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